Bulk 98 feem pua Phloretin Powder yog ib hom tshiab ntawm cov tawv nqaij dawb huv tsis ntev los no tshawb fawb thiab tsim tawm txawv teb chaws. Nws yog tsuas yog los ntawm tev ntawm txiv apples. Nws yog dav siv nyob rau hauv lub ntsej muag lub ntsej muag, daim tawv nqaij cream, lotions thiab essences. Nws tuaj yeem cuam tshuam qhov tso tawm ntau dhau ntawm cov qog sebaceous rau kev kho pob txuv exuberant; Nws tuaj yeem cuam tshuam cov kev ua ntawm melanocytes thiab muaj kev cuam tshuam rau ntau yam tawv nqaij pigmentation. Piv nrog cov khoom xyaw ntuj zoo sib xws arbutin thiab kojic acid, tib lub ntsiab lus ntawm phloretin tau zoo dua inhibitory nyhuv ntawm tyrosinase, thiab thaum nws yog compounded nrog arbutin thiab (los yog) kojic acid, nws muaj peev xwm inhibit tyrosinase. Zoo heev txhim kho cov khoom lag luam inhibition ntawm tyrosinase, thiaj li ua tiav cov txiaj ntsig ntawm whitening. Phloretin muaj cov nyhuv moisturizing zoo heev, tuaj yeem nqus tau 4 mus rau 5 npaug ntawm nws tus kheej qhov hnyav ntawm cov dej, tuaj yeem txhawb nqa kev nqus thiab siv lwm yam khoom siv hauv cov mis, kom nws tuaj yeem ua tau zoo dua; nws txoj haujlwm antioxidant kuj muaj zog heev, tuaj yeem tshem tawm cov tawv nqaij dawb radicals hauv. Cia peb kawm txog nws ua ke!
1. Kev tiv thaiv kev laus thiab kev ua haujlwm antioxidant
Nws yog ib qho flavonoid ntawm dihydrochalcone qauv nrog 4 phenolic hydroxyl pawg, thiab nws cov qauv tshwj xeeb txiav txim siab nws cov haujlwm muaj zog antioxidant. Hauv vitro kev sim qhia tias nws muaj peev xwm inhibit mitochondrial lipid peroxidation, tshem tawm DPPH dawb radicals thiab ABTS dawb radicals.
Cov kev tshawb fawb tau pom tias nws muaj zog antioxidant kev ua haujlwm, nrog rau cov tshuaj tua kab mob antioxidant ntawm 10.30 mg / L rau roj, uas tuaj yeem tshem tawm cov dawb radicals hauv daim tawv nqaij. Nws tsis tsuas yog muaj cov nyhuv antioxidant ntawm nws tus kheej, tab sis kuj tuaj yeem siv ua ke nrog cov antioxidants uas twb muaj lawm los txhim kho cov nyhuv antioxidant. Txoj kev tshawb nrhiav pom tias kev sib xyaw ua ke ntawm 34.9 feem pua ferulic acid, 35.1 feem pua phloretin, thiab 30 feem pua ntawm cov dej-soluble V muaj cov nyhuv antioxidant. Nyob rau tib lub sijhawm, cov kws tshawb fawb tau daws cov teeb meem ntawm cov dej tsis zoo solubility thiab kev ruaj ntseg ntawm nws los ntawm kev siv O / W microemulsion technology thiab embedding technology, muab kev taw qhia rau nws daim ntawv thov hauv tshuaj pleev ib ce. Nws tuaj yeem pom tias zoo98% Phloretin hmoovmuaj cov txiaj ntsig zoo dawb radical scavenging thiab muaj cov ntawv thov zoo hauv cov tshuaj pleev ib ce los tiv thaiv kev laus.
2. Anti-inflammatory kev ua
Cov kev tshawb fawb hauv vitro tau pom tias nws tuaj yeem cuam tshuam kev tsim cov inflammatory yam, chemokines thiab sib txawv yam, thiab muaj qee yam kev tiv thaiv kab mob. Nyob rau tib lub sijhawm, txoj kev tshawb nrhiav pom tias nws tuaj yeem cuam tshuam cov phosphorylation ntawm ib leeg Akt thiab MAPK, thiaj li ua tiav cov nyhuv anti-inflammatory. Nws kuj tau pom tias muaj cov tshuaj tua kab mob antioxidant thiab tiv thaiv kab mob hauv cov kev tshawb fawb vivo. Nws cov tshuaj tiv thaiv kab mob hauv vitro thiab hauv vivo qhia tias nws muaj peev xwm soothing nyhuv thiab tuaj yeem siv rau hauv cov khoom tu tawv nqaij soothing.
3. Kev tiv thaiv tshav ntuj
Cov kev tshawb fawb tau pom tias nws muaj peev xwm nqus tau ultraviolet rays, thiab ntxiv nws rau cov qauv ntawm cov tshuaj pleev ib ce tuaj yeem txhim kho SPF thiab SPA qhov tseem ceeb ntawm cov tshuaj pleev ib ce. Tsis tas li ntawd, phloretin, V thiab ferulic acid sib xyaw tiv thaiv tib neeg cov tawv nqaij los ntawm UV rays thiab muab photoprotection rau tib neeg daim tawv nqaij. Nws tuaj yeem tsis tsuas yog nqus cov kab hluav taws xob ncaj qha xwb, tab sis kuj tseem txhim kho cov kev qhia ntawm nucleotide excision kho noob, ua kom qeeb ntawm cov pyrimidine dimers, glutathione degradation thiab cell tuag vim UVB, thiab txo qhov kev puas tsuaj ntawm ultraviolet rays rau keratinocytes.
Cov hluav taws xob ultraviolet tuaj yeem ua rau cov hlwb los tsim cov pa oxygen reactive thiab dawb radicals, uas tsis ruaj tsis khov thiab ua rau muaj cov kab mob oxidative saw uas ua rau cov hlwb puas. Nws muaj cov haujlwm antioxidant thiab absorbs ultraviolet rays, thiab muaj peev xwm siv tau cov nqi hauv tshuaj pleev thaiv hnub tshuaj pleev ib ce.
4. Txhawb transdermal absorption
Nws yog lipophilic compound uas nkag mus rau hauv daim tawv nqaij ntawm intercellular lipids. Cov kev tshawb fawb tau pom tias nws hloov cov membrane dipole muaj peev xwm ntawm phospholipid bilayer, cuam tshuam rau lub koom haum interfacial ntawm phospholipid bilayer thiab osmotic-tsav dej dynamics ntawm dej. Cov tshuaj muaj txiaj ntsig zoo transdermal.
Nyob rau tib lub sijhawm, thaum nws tau siv los ua qhov nruab nrab, qhov kev nqus ntawm cov lidocaine hydrochloride tau nce mus rau 5.4 npaug ntawm qhov qub, qhia tias nws tuaj yeem cuam tshuam cov txheej txheem thauj mus los ntawm tus neeg nqa khoom thiab muaj qee yam haujlwm ntawm kev txhawb nqa transdermal absorption. Nws yog ib qho ntuj, muaj kev nyab xeeb thiab zoo lipophilic compound nrog rau qee yam cuam tshuam los txhawb kev nkag mus. Nws tuaj yeem muab ntxiv rau cov tshuaj pleev ib ce raws li tus neeg nqa khoom ntawm cov khoom xyaw uas muaj txiaj ntsig zoo los txhawb lub transdermal nqus ntawm cov khoom xyaw nquag thiab ua kom nws ua lub luag haujlwm zoo dua. nyhuv.
5. Antibacterial kev ua haujlwm
Nws yog flavonoid compound nrog bacteriostatic kev ua haujlwm. Txoj kev tshawb nrhiav pom tias nws muaj zog inhibitory cuam tshuam rau cov kab mob Gram-zoo, tshwj xeeb tshaj yog nyob rau Staphylococcus aureus (ATC6538, MIC=7.81 mg/L), Listeria (ATCC 13932, MIC=62.5 mg. /L) thiab murine Salmonella typhi (ATCC 13111, MIC=125 mg/L). Ntxiv nrog rau nws txoj haujlwm bacteriostatic tawm tsam cov kab mob pathogenic, nws kuj muaj kev cuam tshuam rau cov kab mob hauv daim tawv nqaij. Nws MIC rau Propionibacterium acnes thiab P. acnes granules yog ob qho tib si 0.5 mg/L, thiab cov txiaj ntsig kev soj ntsuam tau pom tias cov neeg mob muaj cov pob khaus loj, cov taub hau dub, papules thiab sebum secretion tom qab siv nws li 4 lub lis piam. , qhia tias nws muaj peev xwm pob txuv-relieving nyhuv.
Ntawm qhov tod tes, nws cov nyhuv inhibitory ntawm cov kab mob yog ua rau cov enzyme protein system hauv cov kab mob, cuam tshuam rau lub zog metabolism ntawm cov kab mob thiab oxidative puas tsuaj kho cov kab mob loj hlob; ua rau cov kab mob tuag taus. Piv txwv li, nws muaj qee yam bacteriostatic nyhuv. Nrog rau qhov kev kawm tob ntawm nws cov nyhuv bacteriostatic, nws tuaj yeem tsim los ua tus neeg sawv cev tshiab bacteriostatic ntxiv rau cov tshuaj pleev ib ce los hloov qee cov tshuaj tua kab mob, thiab tseem tuaj yeem siv los ua cov tshuaj tua kab mob ntuj. Cov khoom xyaw ua haujlwm tau ntxiv rau cov tshuaj pleev ib ce tiv thaiv pob txuv.
6. Kev ua kom dawb huv
Cov kev tshawb fawb tau pom tias nws muaj cov nyhuv inhibiting tyrosinase kev ua, thiab nws cov Ic∞ yog 37.5 txmol / L. 0.3 feem pua ntawm nws qhov inhibition tus nqi ntawm tyrosinase yog siab li 98.2 feem pua, thiab nws inhibition ntawm amino acid yog zoo dua li ntawm cov tshuaj dawb (kojic acid thiab arbutin). Kev tshawb fawb ntxiv pom tias nws yog piv rau cov tyrosinase Inhibitor compounding tuaj yeem txhim kho nws qhov inhibition npaum li cas, thiab ua tiav 100 feem pua inhibition nyhuv zoo. Tsis tas li ntawd, qhov sib xyaw ua ke ntawm hydroxypropyl cyclodextrin thiab nws kuj muaj qhov cuam tshuam zoo rau kev ua haujlwm ntawm tyrosinase.
7. Moisturizing
4 pawg hydroxyl muaj nyob rau hauv nws cov molecule tuaj yeem tsim hydrogen bonds nrog dej molecules kom nqus dej thiab muaj peev xwm moisturizing. Yog li ntawd, 98 feem pua Phloretin Powder rau kev muag khoom kuj tuaj yeem siv los ua cov khoom siv ntuj tsim hauv cov tshuaj pleev ib ce moisturizing.
8. Cov nyhuv tiv thaiv plaub hau
Cov kev tshawb fawb tau pom tias nws tuaj yeem cuam tshuam cov kev ua ntawm cov taum pauv lipoxygenase, yog li txo cov plaub hau poob vim kev laus ntxov ntxov, qhia tias nws muaj peev xwm tiv thaiv plaub hau poob thiab tuaj yeem ntxiv rau cov tshuaj zawv plaub hau thiab tshuaj pleev ib ce raws li kev tiv thaiv plaub hau. khoom.
9. Antitumor kev ua
Cov kev tshawb fawb tau pom tias nws induces qog cell apoptosis los ntawm inhibiting kev thauj cov piam thaj hauv cov qog hlwb. Cov kev tshawb fawb tau pom tias nws tuaj yeem cuam tshuam kev loj hlob ntawm cov qog nqaij hlav cancer thiab ua rau lawv cov apoptosis nyob rau hauv ib qho concentration- thiab nyob ntawm lub sij hawm. Nws tuaj yeem thaiv lub voj voog ntawm tes hauv G1 theem, los ntawm kev cuam tshuam lub voj voog ntawm tes, txo cov mitochondrial membrane peev xwm, thiab hloov cov calcium ion tshuav nyiaj li cas intracellular. Induce apoptosis ntawm cov qog nqaij hlav cancer.
10. Txhim kho vascular endothelial dysfunction thiab mob
Cov pab pawg neeg choline siab dua hauv lwm pab pawg tuaj yeem txo cov ntshav cov roj (cholesterol) tag nrho, triacylglycerol, alanine aminotransferase, aspartate aminotransferase, endothelin-1 thiab thromboxane A2, thiab ua rau muaj kev cuam tshuam loj ntawm cov ntshav prostacyclin thiab TSIS TAU. Txhim kho vascular endothelial muaj nuj nqi. Tsis tas li ntawd, nws tuaj yeem txhim kho cov kev ua ub no ntawm superoxide dismutase thiab glutathione peroxidase hauv daim siab, txo cov qib ntawm malondialdehyde, thiab cov kev sim histopathological kuj pom tias muaj kev tiv thaiv ntawm daim siab.
Lwm cov kev tshawb fawb tau pom tias nws tuaj yeem ua rau cov ion channel hauv cov hlwb, inhibit qhov nkag ntawm calcium ions los ntawm cov calcium uas muaj peev xwm ua tau los ntawm kev tso tawm calcium ions los ntawm endoplasmic reticulum induced los ntawm phosphoinositide 3, yog li cuam tshuam rau qhov contraction ntawm lub aorta, ua lub luag haujlwm tiv thaiv cov hlab ntsha.
11. Kev txhawb nqa kev nqus nqus
Nws yog ib qho lipophilic compound, thiab nws muaj qee yam cuam tshuam rau ntawm cov cell membrane, uas tuaj yeem cuam tshuam rau cov txheej txheem thauj mus los. Cov kev tshawb fawb tau pom tias nws tuaj yeem cuam tshuam cov kev ua ntawm melanocytes, muaj cov nyhuv lightening ntawm ntau yam tawv nqaij pigmentation, thiab muaj cov nyhuv inhibitory zoo ntawm tyrosinase. Nws yog ib qho kev nyab xeeb thiab ua tau zoo freckle whitening tus neeg sawv cev. Nyob rau hauv vitro tyrosinase kev ua si kuaj Nws tau pom tias nws inhibited tyrosinase kev ua si hauv kev sib tw thiab kev siv tshuaj ntau npaum li cas.
Peb yog98 feem pua ntawm Phloretin Powder lwm tus neeg. Txhua pawg ntawm cov khoom tuaj yeem xa tuaj rau koj tom qab kev tshuaj xyuas nruj. Yog xav paub ntxiv, thov hu rau thiab nug peb tam sim ntawd, koj qhov kev txaus siab yog peb qhov tseem ceeb tshaj plaws. Ua tsaug!
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