Kojic acid, lub npe tshuaj yog 5-hydroxy-2-hydroxymethyl-1, 4-pyrone, muaj nyob rau hauv cov kua ntses, taum paste, thiab cawv, thiab tuaj yeem kuaj pom Hauv ntau cov khoom fermented fermented nrog Aspergillus nws muaj. Nws yog ib qho tsis muaj zog acid compound tsim los ntawm fermentation nrog me me molecular hnyav, uas tuaj yeem nqus ncaj qha los ntawm daim tawv nqaij thiab muaj kev siv siab. Nws tuaj yeem tiv thaiv kev tsim cov tyrosinase, yog li inhibiting zus tau tej cov melanin, thiab thaiv cov zus tau tej cov melanin. Cia peb kawm txog nws ua ke!
Whitening mechanism:
Lub tshuab ntxuav hniav dawb ntawm Pure99% Kojic Acid Powderyog kom ncaj qha inhibit lub tyrosinase uas ua rau melanin melanin, tiv thaiv melanin melaninization (polymerization).
Nyob rau hauv daim tawv nqaij irradiated nrog ultraviolet rays, tyrosine amino acids nyob rau hauv melanocytes ntawm lub basal txheej ua ke nrog lub tyrosinase active enzyme ua dopa, thiab tom qab lub dopa khi rau lub tyrosinase, nws ua dopaquinone, ib feem ntawm dopaquinone ua eumelanin (melanin). ).
Lub tshuab ntxuav hniav dawb ntawm Cov Lag Luam wholesale 99 feem pua Kojic Acid Powder yog txhawm rau ntxiv cov tooj liab tsim nyog rau kev ua haujlwm ntawm tyrosinase los thaiv cov haujlwm ntawm tyrosinase thiab tiv thaiv nws los ntawm kev sib cuag nrog tyrosine, yog li inhibiting tyrosinase Nws muaj cov nyhuv inhibiting ntawm DHICA thiab DHI, lub ntsiab precursor monomers ntawm melanin, kom ua tiav cov nyhuv ntawm whitening thiab kev tu tawv nqaij.
Kojic acid kev nyab xeeb:
Nyob rau thaum ntxov 1990s, Nyiv tau ua tus thawj coj hauv kev ntxiv kojic acid rau cov tshuaj pleev ib ce ua cov khoom ua kom tawv nqaij, feem ntau yog siv nws cov nyhuv inhibitory ntawm tyrosinase thiab thaiv ntawm melanin ntau lawm intermediates kom whiten daim tawv nqaij thiab tshem tawm pigmentation. Cov kev tshawb fawb tom qab pom tias nws yuav muaj kev pheej hmoo carcinogenic. Xyoo 2003, tsoomfwv Nyij Pooj tau txwv tsis pub ntshuam thiab rov tsim cov tshuaj pleev ib ce uas muaj kojic acid. Tom qab ntawd, vim muaj pov thawj tsis txaus, cov kev cai rau kev ntxiv nws rau cov tshuaj pleev ib ce tau rov qhib dua xyoo 2005. Txawm hais tias tsis muaj kev txwv meej rau kev siv, nws raug pom zoo tias qhov ntau npaum li cas ntawm 0.1 feem pua thiab 1 feem pua ntawm qhov loj feem.
Toxicity kinetic kev tshawb fawb hauv nas pom tau hais tias kojic acid sai sai absorbed thiab faib mus rau ntau yam kab mob tom qab lub qhov ncauj, dermal los yog subcutaneous tswj, thiab cov metabolic tus nqi ntawm qhov ncauj thiab subcutaneous tswj yog sai dua li ntawm daim tawv nqaij raug, thiab cov metabolites mas sulfuric acid thiab. qabzib. Conjugates ntawm uronic acid thiab kojic acid metabolites muaj nyob rau hauv daim siab thiab ob lub raum thiab tsuas yog tawm hauv cov zis. Nyob rau hauv xyoo tas los no, ntau tus kws tshawb fawb txawv teb chaws tau ua ntau yam kev tshawb fawb txog nws cov genotoxicity, carcinogenicity, embryotoxicity thiab teratogenicity, thiab mutagenicity ntawm cov khoom siv caj ces. Hauv qhov ntau ntawm 1000-l500 mg/kg. Nyob rau hauv qhov ntau ntawm qhov ncauj koob tshuaj ntawm 300-1000 mg/(kg·d), txawm nyob rau hauv cov txiv neej los yog poj niam nas, ntau yam kev soj ntsuam physiological thiab biochemical indicators, As, tsis muaj tshwm sim nyob rau hauv necropsy thiab microscopic soj ntsuam, tsuas yog lymphocytes thiab leukocytes. . qis dua. Txoj kev tswj hwm ntawm intraperitoneal tau siv, thiab koob tshuaj kojic acid yog 300 mg / kg txhua zaus. Tom qab 14 hnub, nas tau tsim hepatotoxicity thiab pathological tshwm sim. Txawm li cas los xij, cov txiaj ntsig ntawm kev tshawb fawb txog nws cov teebmeem ntawm fertility thiab embryos hauv nas yog tsis paub tseeb.
Txawm hais tias kojic acid muaj cov nyhuv mutagenic ntawm cov khoom siv caj ces ntawm cov kab mob, tshwj tsis yog tias nws tuaj yeem ua rau muaj kev hloov pauv hauv cov noob ntawm qee hom kab mob Salmonella thiab Bacillus subtilis, cov kws tshawb fawb sib txawv tau txais cov lus sib txawv. Ntau cov kev tshawb fawb tau pom tias nws ua rau cov thyroid hyperplasia ywj siab ntawm txoj kev genotoxic. Kev noj tshuaj ntau ntxiv tuaj yeem cuam tshuam qhov nqus ntawm iodine hauv nas thiab nas, thiab ua rau cov thyroid hyperplasia thiab adenoma. Ntxiv kojic acid rau zaub mov yuav muaj kev pheej hmoo ua rau cov qog qog nqaij hlav, tab sis qhov kev sim tam sim no tsuas yog rau cov nas thiab nas, thiab tsis muaj lwm yam pov thawj ntawm cov tsiaj txhu. Txawm li cas los xij, qhov concentration ntawm kojic acid nyob rau hauv cov zaub mov yog tsawg heev, thiab nws yuav tsum muaj kev nyab xeeb siv nyob rau hauv ib txwm muaj xwm txheej.
Main functions thiab siv
1. Siv hauv kev lag luam los ua cov tshuaj pleev ib ce
Nws tuaj yeem cuam tshuam cov synthesis ntawm tyrosinase, yog li nws tuaj yeem tiv thaiv kev tsim ntawm daim tawv nqaij melanin, thiab nws muaj kev nyab xeeb thiab tsis muaj tshuaj lom, thiab yuav tsis tsim cov vitiligo sequelae, yog li nws tau raug tsim rau hauv cov tshuaj pleev ib ce, qhov ncauj qhov ntswg, tshuaj pleev ib ce, thiab tshuaj pleev ib ce. . Cov tshuaj pleev ib ce muaj txiaj ntsig zoo uas kho cov pob txuv, hnub nyoog me ntsis, hyperpigmentation, pob txuv, thiab lwm yam. Ntawm qhov siab ntawm 20ug / ml, nws tuaj yeem inhibit 70-80 feem pua ntawm cov dej num ntawm ntau yam tyrosinase (los yog polyphenol oxidase PPO), thiab tus nqi ntxiv hauv cov tshuaj pleev ib ce yog 0.5-2.0 feem pua .
2. Rau kev ua zaub mov
99 feem pua Kojic Acid Powder rau muag tuaj yeem siv los ua zaub mov ntxiv rau kev khaws cia, tshuaj tua kab mob thiab tiv thaiv oxidation. Kev sim tau pom tias nws tuaj yeem cuam tshuam kev hloov pauv ntawm sodium nitrite hauv nqaij npuas kib rau hauv cov khoom noj carcinogenic nitrosamines, thiab ntxiv rau cov zaub mov yuav tsis cuam tshuam rau saj, aroma thiab kev ntxhib los mos ntawm cov zaub mov; Nws tseem yog cov khoom siv raw rau kev tsim cov maltol thiab ethyl maltol. Hauv kev ua zaub mov, daim ntawv thov ntau yog dav heev.
3. Rau kev siv tshuaj
Txij li nws tsis muaj qhov cuam tshuam rau cov hlwb eukaryotic, nws tseem tuaj yeem tshem tawm cov dawb radicals hauv tib neeg lub cev thiab txhim kho lub zog ntawm cov qe ntshav dawb, uas muaj txiaj ntsig zoo rau tib neeg kev noj qab haus huv. Yog li ntawd, nws tau raug siv los ua cov khoom siv raw ntawm cov tshuaj tua kab mob cephalosporin, thiab cov tshuaj tiav ua tiav yog siv rau kev kho mob taub hau, Hniav thiab mob hauv zos thiab lwm yam kab mob, cov tshuaj analgesic thiab anti-inflammatory teebmeem yog qhov zoo tagnrho.
4. Agricultural tshuaj tua kab
Nws tuaj yeem siv los tsim cov tshuaj tua kab mob lom. Cov tshuaj lom neeg micro-fertilizer (cov kua liab tsaus) ua los ntawm kev ntxiv 0 5-1 0 feem pua kojic acid, txawm tias nws yog txau ntawm qhov qis qis raws li foliar chiv, lossis ua rau hauv ib tug loj hlob thiab yield-nce tus neeg sawv cev rau hauv paus daim ntawv thov, no qoob loo zus txhawb nqa yog zoo rau cov zaub mov thiab zaub muaj cuab kev ntawm nce yield.
Peb Cov 99 feem pua Kojic Acid Powder yog cov khoom zoo nrog cov khoom txaus. peb lav peb cov khoom raug tsim nyob rau hauv nruj raws li tus qauv thiab specification. Peb niaj hnub tsim ntau cov khoom kom tau raws li kev xav tau ntawm kev lag luam, yog tias koj muaj kev xav tau, thov hu rau peb dawb. Email:info@lonierherb.comWhatsapp / Wechat: ntxiv rau 86-18189137076
