Protocatechuic acid (PCA) yog dab tsi?
Ntau cov palatable thiab kho cov nroj tsuag muaj cov dihydroxybenzoic phenolic tivthaiv hu uaProtocatechuic Acid(PCA). Thaum kuaj siv 1,1-diphenyl-2-picrylhydrazyl radical scavenging kev ua ub no, nws yog thawj metabolite ntawm antioxidant polyphenols uas muaj nyob rau hauv ntsuab tshuaj yej (IC50=16.3 μM) thiab qhia lub peev xwm. kom tshem tawm cov dawb radicals. Nws cov tshuaj tiv thaiv kab mob, tiv thaiv hyperglycemic, neuroprotective, thiab tiv thaiv qog noj ntshav tau lees paub zoo. Qhia txog pro-apoptotic thiab anti-proliferative zog nyob rau hauv ntau cov ntaub so ntswg thiab inhibits tshuaj carcinogenesis nyob rau hauv vitro nyob rau hauv PCA dependence.
Protocatechuic acid (PCA) cov txiaj ntsig
1. Antibacterial nyhuv
Ntau cov kab mob kis tau raug cuam tshuam los ntawm inhibitory cuam tshuam ntawm protocatechuic acid, suav nrog methicillin-resistant hom Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, thiab Acinetobacter baumannii.
2. Anticancer nyhuv
Protocatechuic AcidNws muaj peev xwm tiv thaiv cov qog nqaij hlav cancer los ntawm metabolizing, txo lawv cov invasiveness, thiab txhawb cov qog nqaij hlav cancer hauv tib neeg lub mis, ntsws, siab, ncauj tsev menyuam, thiab prostate. Nws txo qis kev muaj peev xwm ntawm cov qog nqaij hlav qog noj ntshav thiab yog nyob ntawm qhov concentration. Qhov no qhia tau hais tias yuav ua li cas protocatechuic acid ua haujlwm tiv thaiv qog noj ntshav los ntawm kev ua rau cov qog nqaij hlav cancer tuag lossis ncua lawv cov khoom noj thiab cov metabolism. Nws tuaj yeem ua tus neeg sawv cev tiv thaiv kab mob.
3. Antioxidant nyhuv
Alpinia zingiberensis protocatechuic acid inhibits oxidative kev puas tsuaj, txo tus nqi ntawm cell ciaj sia nyob rau hauv vitro los ntawm hydrogen peroxide, thiab yuav txo tau oxidative kev nyuaj siab nyob rau hauv vivo. Nws cov khoom siv tshuaj tiv thaiv oxidative thiab muaj peev xwm los txwv kev tsim cov dawb radicals tuaj yeem yog lub hauv paus ntawm nws cov kev tiv thaiv. Hibiscus sibiricum protocatechuic acid tiv thaiv hepatocytes tiv thaiv oxidative puas los ntawm t-BHP. Nyob rau hauv nas plawv cov ntaub so ntswg, protocatechuic acid exerts ib tug tiv thaiv nyhuv ntawm histopathological thiab oxidative puas los ntawm dioxin. Los ntawm kev txo qis glutathione, catalase, glutathione peroxidase, thiab superoxide dismutase hauv dioxin-induced nas plawv cov ntaub so ntswg thiab nce qib ntawm thiobarbituric acid active tshuaj, nws txo cov necrosis thiab los ntshav ntawm lub plawv cov ntaub so ntswg.
4. Anti-inflammatory nyhuv
Protocatechuic acid muaj cov nyhuv anti-inflammatory. Nws muaj kev tiv thaiv ntawm LPS-induced RAW-264.7 hlwb thiab lub hnab cua qauv ntawm cov nas induced los ntawm caraway gum, thiab tuaj yeem txo cov proinflammatory yam TNF- , IL-1 , proinflammatory mediators TSIS TAU, PGE2, INOS, COX-2, NF-κB thiab MAPK
5. Anti-hyperglycemic nyhuv
Cov teeb meem ntshav qab zib txuas nrog glycation tuaj yeem zam lossis txo qis nrog kev siv cov tshuaj protocatechuic acid.
Hauv cov nas uas muaj ntshav qab zib mellitus, protocatechuic acid tau nce qib insulin thiab txo cov ntshav qabzib.
Dab tsi yog kev siv ntawm protocatechuic acid?
01 Kev Kho Mob Nruab Nrab: Tus Pabcuam Tseem Ceeb hauv Tshuaj Tiv Thaiv Kab Mob
Txhawm rau tsim cov tshuaj tiv thaiv kab mob uas muaj zog tiv thaiv kab mob, protocatechuic acid, cov khoom siv hluavtaws pib rau cov tshuaj tiv thaiv kab mob erlotinib, yuav tsum mus dhau ntau txoj haujlwm hnyav xws li etherification thiab nitration. Qhov kev tshawb pom no tau muab kev kho mob qog noj ntshav tshiab kev cia siab thiab muab ntau tus neeg mob nkag mus rau kev xaiv kho mob. Nws kuj tseem ua lub luag haujlwm tseem ceeb hauv kev kho mob ntawm cov kab mob ua pa, kab mob sib kis, thiab cov kab mob lom lom vim nws cov teebmeem ntau, suav nrog kev ua kom tshem tawm, expectorant, antibacterial, thiab antiasthmatic zog.
02 Cosmetics Field: Muaj peev xwm loj hauv daim tawv nqaij Anti-wrinkle thiab Anti-aging
Protocatechuic acid yog lub ntuj muaj zog antioxidant uas tuaj yeem tiv thaiv oxidative kev ntxhov siab vim ua rau daim tawv nqaij puas thiab neutralize dawb radicals. Ntxiv nrog rau kev ua kom qeeb ntawm cov txheej txheem kev laus ntawm daim tawv nqaij, nws pab tiv thaiv daim tawv nqaij los ntawm oxidative kev nyuaj siab los ntawm lwm qhov chaw xws li cov pa phem, UV hluav taws xob, thiab oxides.
03 Pub Additive: Tus Saib Xyuas Kev Noj Qab Haus Huv Tsiaj
Protocatechuic acid nthuav tawm nws cov txiaj ntsig tshwj xeeb hauv kev lag luam tsiaj thiab. Protocatechuic acid tuaj yeem txhawb kev tiv thaiv kab mob, txhim kho nqaij zoo thiab tsw, txhawb kom tsiaj loj hlob thiab kev loj hlob, thiab nce kev siv khoom noj thaum ntxiv rau pub. Nws tuaj yeem ua rau kev lag luam aquaculture nce nyiaj txiag nce ntxiv thaum tib lub sijhawm tswj kev noj qab haus huv ntawm cov tsiaj.
04 Cov Khoom Tshiab Hloov Bisphenol A: Tus Tshiab Nyiam hauv Aerospace
Kev lag luam tau ntev dhau los nrog kev txhawj xeeb txog kev nyab xeeb nyob ib puag ncig bisphenol A. Nyob rau hauv thaj chaw ntawm cov ntaub ntawv tshiab, protocatechuic acid nthuav tawm cov lus cog tseg zoo kawg nkaus li kev hloov pauv tau. Nws tuaj yeem tsim cov ntaub ntawv nrog qhov sib txawv ntawm qhov sib txawv siab, uas txhim kho cov khoom siv thermal stability, cuam tshuam rau lub zog, thiab elongation ntawm kev tawg ua tsaug rau nws cov pab pawg tshwj xeeb, xws li hydroxyl thiab carboxyl pawg. Ntau yam kev siv hauv kev lag luam aerospace yog ua tau los ntawm kev ua tau zoo ntawm protocatechuic acid hloov acrylate resin.
05 Synthesis of Vanillin: Ib Yam Khoom Tseem Ceeb hauv Kev Lag Luam Khoom Noj thiab Spice
Protocatechuic acid yog ib qho tseem ceeb raw khoom nyob rau hauv kev tsim ntawm vanillin, ib tug tshuaj uas yog dav siv nyob rau hauv ua noj ua haus, cosmetic, thiab txuj lom industries. Vanillin tuaj yeem tsim los ntawm protocatechuic acid los ntawm cov txheej txheem tshuaj lom neeg, muab cov khoom siv zoo ib yam rau kev loj hlob ntawm kev lag luam cuam tshuam. Vanillin tus ntxhiab tsw thiab ruaj khov ua rau muaj txiaj ntsig zoo rau kev txhim kho cov khoom zoo thiab cov neeg siv kev paub.
Raws liProtocatechuic Acidcov tuam txhab, LonierHerb tau paub txog cov txheej txheem ntau lawm, txhua xyoo, muaj ntau yam khoom xa tuaj thoob ntiaj teb. Yog tias koj txaus siab, thov hu rau peb dawb. Email:info@lonierherb.comWhatsapp / Wechat: +86-18189137076
