Pterostilbene hmoov yog dab tsi?
Lub active tivthaiv pterostilbene muaj nyob rau hauv cov txiv hmab txiv ntoo xws li txiv hmab txiv ntoo, bilberries, thiab blueberries. Nyob rau hauv cov nroj tsuag, nws muaj ib tug anti-toxin muaj nuj nqi. Pterostilbene yog trans-stilbene molecule uas sib koom cov qauv zoo sib xws nrog resveratrol. Nws yog ib qho methylated derivative ntawm resveratrol. Pterostilbene ua tau zoo nce bioavailability vim nws muaj ob pawg methoxy uas pab txhawb kev nqus. Nws muaj ntau yam khoom siv lom neeg, suav nrog lipid-txo, tshuaj tua kab mob, tiv thaiv qog, tiv thaiv kab mob, thiab antioxidant zog. Yog li ntawd, nws yog dav siv nyob rau hauv ntau lub lag luam, nrog rau cov khoom noj, tshuaj pleev ib ce, thiab tshuaj.
Pterostilbene vs Resveratrol
1) Resveratrol thiab pterostilbene sib koom cov qauv molecular zoo sib xws thiab cov txheej txheem ntawm kev ua. Antioxidant resveratrol pab tiv thaiv kev puas tsuaj los ntawm cov dawb radicals. Pterostilbene, uas muaj ob qho methylation derivatives "kos" hauv nws cov qauv, yog ib qho derivative uas ruaj khov dua, muaj bioavailability zoo dua, thiab muaj kev cuam tshuam antioxidant zog dua li resveratrol.
2) Pterostilbene muaj cov tshuaj tua kab mob ntau dua li resveratrol vim nws cov qauv sib txawv. Tsis tas li ntawd, pterostilbene muaj ntau dua antioxidant thiab ruaj khov hauv lub cev dua li resveratrol.
3) Pterostilbene muaj ob pawg methoxy uas pab txhawb kev nqus, uas txhawb nqa bioavailability. Nws bioavailability hauv cov tsiaj kuaj tau pom tias muaj kwv yees li 80%, thaum resveratrol yog kwv yees li 20%. Pterostilbene yog ntau soluble nyob rau hauv roj ua tsaug rau nws ob pawg methoxy, thiab nws dissolves zoo nyob rau hauv cov roj polar, uas ua rau nws ib tug yooj yim cov khoom xyaw rau roj-theem cov khoom.
Cov txiaj ntsig ntawm pterostilbene hmoov yog dab tsi?
Cov txiaj ntsig rau daim tawv nqaij
01 Antioxidant
Pterostilbene hmoovbulk muaj zog antioxidant zog. Nws yog qhov zoo tshaj plaws cog cov khoom xyaw rau cov tshuaj pleev ib ce ntawm cov khoom siv tawv nqaij thaum nws los txog rau kev tiv thaiv oxidation thiab whitening.
02 Inhibit tyrosinase
Tyrosinase yog lub luag haujlwm tseem ceeb hauv kev tsim cov tshuaj melanin. Ib nrab-inhibitory concentration IC50 tus nqi ntawm glabridin, hu ua "whitening kub", ntawm tyrosinase yog qhov qis tshaj ntawm tag nrho cov khoom. Pterostilbene yog me ntsis qis dua glabridin, tab sis zoo dua li lwm yam khoom siv ntxuav hniav dawb xws li VC thiab arbutin.
03 inhibit melanin
Nws muaj qhov muaj zog heev los tiv thaiv melanin, txawm tias ua tau zoo "whitening gold" glabridin, thiab nws txo qis freckles.
04 Anti-inflammatory
Nws tuaj yeem cuam tshuam qhov kev qhia ntawm COX-2, iNOS, PGE2 thiab NO los ntawm txoj kev Nrf2 thiab txo qis qhov mob. Muaj qee cov enzymes puas tsuaj hauv tib neeg lub cev, xws li elastase thiab collagenase, uas tuaj yeem rhuav tshem cov qauv ntawm daim tawv nqaij, ua rau daim tawv nqaij sag thiab hnub nyoog. Pterostilbene muaj ob lub peev xwm inhibitory, inhibiting ob lub enzymes puas tsuaj tib lub sijhawm, uas tuaj yeem tiv thaiv wrinkles thiab ncua kev laus, thiab txhim kho qhov teeb meem ntawm xoob wrinkles.
05 Anti-ultraviolet
Tiv thaiv ultraviolet rays thiab tiv thaiv lub teeb puas
Nyob rau hauv txoj kev tshawb no ntawm "Kev tiv thaiv nyhuv ntawm pterostilbene rau mob lub teeb puas ntawm tib neeg fibroblasts tshwm sim los ntawm ntev-yoj ultraviolet hluav taws xob", DNA kev puas tsuaj tsom xam tau ua los ntawm cell viability detection thiab comet assay, thiab nws tau pom hais tias ib tug tej yam kab mob concentration ntawm pterostilbene tau. txo qhov kev puas tsuaj ntawm ultraviolet rays rau HFF hlwb.
Qhov siab tshaj plaws ultraviolet absorption wavelength ntawm pterostilbene yog 306nm, thiab nws qhov nqus siab tshaj plaws npog qhov 280-320nm band (UVB), nrog UVB nqus tau zoo.
06 Anti-glycation
Glycated aging protein (AGE) yog qhov tshwm sim ntawm cov piam thaj dawb hauv lub cev cuam tshuam nrog cov proteins hauv txoj hauv kev los ntawm txoj kev Maillard. Cov protein ib txwm raug rhuav tshem thaum lub sijhawm tsim cov txheej txheem AGE protein, uas xaus rau kev rhuav tshem ntawm tes thiab lub neej. Nws cov yam ntxwv ntawm polyhydroxyl ua rau nws sib tw nrog cov pab pawg hydroxyl ntawm cov suab thaj los tsim Schiff hauv paus, tiv thaiv kev tso tawm ntawm qhov hnyav molecular AGE. Nws tseem tuaj yeem tiv thaiv thiab kho AGE glycated aging proteins.
Cov txiaj ntsig kev noj qab haus huv
01 Txhawb kev mob plawv
Kev pheej hmoo ntawm atheroclerosis tuaj yeem txo qis los ntawm kev tswj cov tshuaj antioxidant enzyme SOD, vascular endothelial hlwb, thiab vascular du leeg hlwb.
02 Txhawb kev noj qab haus huv ntawm plab hnyuv
Nws muaj qee yam inhibitory cuam tshuam rau kev loj hlob ntawm cov hlwb tsis zoo nyob rau hauv txoj hlab pas, plab thiab cov hnyuv, thiab txo cov kev tsis zoo ntawm lub plab zom mov.
03 Txhim kho carbohydrate metabolism
Nws txo qis cov kab mob hauv plab tsis zoo thiab muaj qee yam cuam tshuam rau kev loj hlob ntawm cov kab mob pathogenic hauv plab, hnyuv, thiab txoj hlab pas.
04 Txhim kho cov roj metabolism
Nws tuaj yeem txo cov rog cell proliferation thiab triglyceride buildup hauv lub cev hauv 3T3-L1 preadipocytes.
05 Txhim kho daim siab mob
Blueberry extracts, suav nrog pterostilbene, muaj peev xwm txhawb nqa Nrf2 txoj hauv kev thiab antioxidant enzyme ntau lawm. Ib qho kev sim qhia tau hais tias cov neeg siv pterostilbene tau qis dua cov cim qhia cuam tshuam nrog kev mob siab rau lub siab.
06 ncua lub hlwb laus
Nws tuaj yeem ua rau kev nco thiab lub hlwb tsis zoo los ntawm cov tshuaj tiv thaiv kab mob, thiab txo cov hlwb laus.
07 Kev kho mob plawv
Nws tuaj yeem txo qhov kev laus ntawm lub hlwb thiab mob ua rau nco tsis tau nrog rau lub hlwb degradation.
08 Kev tiv thaiv daim siab
Los ntawm kev hloov ntau yam tshuaj tiv thaiv kab mob antioxidant, tiv thaiv kab mob, thiab tiv thaiv kev loj hlob, pterostilbene tuaj yeem txhim kho kev ua haujlwm ntawm daim siab hlwb.
09 Metabolism
Pterostilbene's anti-hyperglycemic thiab antioxidant zog tuaj yeem pab cov neeg mob ntshav qab zib tiv thaiv cov teeb meem los ntawm kev txo qis hyperglycemia thiab cuam tshuam rau lawv lub siab thiab ob lub raum. Los ntawm kev txhawb nqa kev ua haujlwm antioxidant, pterostilbene tuaj yeem txhim kho cov metabolism hauv qabzib. Tsis tas li ntawd, qhov ua kom muaj zog antioxidant uas nws tsim tau tuaj yeem txo qhov kev puas tsuaj uas hyperglycemia's reactive oxygen hom-uas ua rau kev puas tsuaj rau lub cev-tsim.
10 Neuroprotection
Kev laus muaj feem cuam tshuam nrog cov kab mob neurodegenerative, suav nrog Parkinson's thiab Alzheimer's kab mob. Qhov no tshwm sim los ntawm cov neeg laus lub siab oxidative kev nyuaj siab thiab tsis muaj peev xwm antioxidant. Cov kab mob no muaj kev sib txuas ntawm kev laus thiab, thaum lawv pib, yuav ua rau kev laus zuj zus. Antioxidant-nplua nuj txiv hmab txiv ntoo tuaj yeem ua tiav qhov kev ua haujlwm ntawm lub paj hlwb, raws li ntau qhov kev tshawb fawb.
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