Muaj zog flavonoid glycosides xws li hesperidin 95%, uas pom nyob hauv cov txiv ntoo, yog qhov nthuav rau cov neeg uas ua haujlwm hauv kev noj qab haus huv thiab khoom noj. Tej zaum nws yuav zoo rau koj txoj kev noj qab haus huv hauv lwm txoj kev thiab. Tias lub cev tuaj yeem siv thiab siv cov tshuaj no yog qhov tseem ceeb heev rau nws ua haujlwm. YogHesperidin 95%yog ua haujlwm thiab nws tuaj yeem ua tshuaj, peb yuav tsum xam seb qhov twg cuam tshuam rau cov txheej txheem no. Nrog rau yuav ua li cas coj hesperidin 95%, cov ncej blog qhia koj ntau txog cov pob khaus kab, enzymes, thiab lwm yam. Nco ntsoov cov ntsiab lus tseem ceeb no thaum peb pab koj paub seb yuav siv cov khoom ntuj no li cas. Nws zoo dua rau ntau cov teeb meem kev noj qab haus huv tam sim no.
Yuav ua li cas lub plab microbiota cuam tshuam hesperidin 95% nqus?
Microbial metabolism ntawm hesperidin 95%
Lub plab muaj qhov tseem ceeb heev rau kev ua tau zoo hesperidin 95% yog nqus thiab siv los ntawm lub cev. Thaum Hesperidin 95% tau noj, nws feem ntau ua rau nws rau lub plab, uas nws ntsib ntau yam kab mob. Cov kab mob no, tshwj xeeb yog cov los ntawm lub genera bifidobacterium thiab Lactobacillus, muaj cov enzymillus, muaj cov enzyms uas tuaj yeem txiav cov suab thaj hauv hesperetin, uas yog aglyocone. Tus kab mob kab mob yog qhov tsim nyog los txhim kho cov Uptake ntawm 95% ntawm hesperakin vim tias cov hnyuv tuaj yeem siv sijhawm ntau dua li cov glycoside daim ntawv. Cov tib neeg sib txawv yuav muaj cov plab muaj ntau yam sib txawv, uas tuaj yeem cuam tshuam txog cov txheej txheem no zoo li cas rau lawv thiab ua li cas Bioavailable hesperidin 95% yog txhua yam.
PrebiSusichiSiSiSiSe Begisure ntawm Hesperidin 95% nqus
Hesperidin 95%tej zaum yuav zoo rau koj vim tias nws yuav pab tau cov kab zoo loj hlob hauv koj lub plab. Cov kab mob ntau dua tuaj yeem tsoo 95% ntawm hesperidin vim tias cov kev sib raug zoo no uas tau txiaj ntsig ob tog. Qhov no ua rau nws yooj yim dua rau lub cev kom nqus. Noj hesperidin 95% txhua hnub tau pom tias hloov lub plab me microbiota. Qhov no pab kev loj hlob ntawm cov kab mob uas ua rau nws nkag tau. Nws yog qhov yooj yim dua rau lub cev kom tau txais 95% ntawm hesperidin vim tias cov nyhuv prebiotic. Nws kuj tseem yuav pab ua kom lub plab muaj kev noj qab haus huv ntau, uas tuaj yeem yog qhov zoo rau koj hauv kev lwm yam tshaj li cov flavonoid.
Microbial ZUS TAU TEJ COV BOUATORATORAL METABOLITES
Nws tsis yog glycoside tawg uas lub plab cov kab mob ua kom muaj kev cuam tshuam Hesperidin 95% nce. Qee tus kab mob hauv plab tuaj yeem tsoo hesperetin ntxiv kom ua cov tshuaj muaj txiaj ntsig zoo li phenic acids thiab lawv conjugates. Nws yog tau tias cov khoom lag luam kab mob no muaj lawv cov kev cuam tshuam roj ntsha uas ntxiv rau cov txiaj ntsig kev noj qab haus huv ntawm Hesperidin 95%. Cov hom thiab cov nyiaj ntawm cov lwg me me no tuaj yeem hloov pauv raws li tus neeg lub plab cov kab mob. Qhov no ua rau nws nyuaj rau lub cev kom nqus thiab siv hesperidin 95%. Txhawm rau kom nkag siab txog li cas Hesperidin 95% yuav pab koj kev noj qab haus huv thiab kev siv cov kev hloov zoo, koj yuav tsum paub cov kab mob no tshwm sim li cas.
Lub luag haujlwm twg enzymatic hloov dua ua si hauv Hesperidin 95% Bioavailability?
Plab hnyuv -} glucosidase kev ua si
Enzymatic hloov yog qhov tseem ceeb heev rau kev ua hesperidin 95% bioavailable. Ib qho tseem ceeb enzyme hauv cov txheej txheem no yog hnyuv- glucosidase tawm ntawm 95% ntawm hesperetin, uas yog aglyocone. Qhov kev hloov no tseem ceeb heev vim tias hesperetin yog ntau li hesperidin 95%, uas txhais tau tias nws tuaj yeem nqus tau zoo dua los ntawm cov plab zom zaws. Txoj haujlwm ntawm {- Glucosidase tuaj yeem sib txawv rau txhua tus neeg vim muaj noob caj noob ces thiab khoom noj, uas yuav tsum ua tau zoo npaum li cas hesperidin 95% yog nqus tau. Tsis tas li, qee qhov chaw noj mov, nyiam lwm cov polyphenols, yuav cuam tshuam nrog cov enzymes no, uas tuaj yeem txo qis tag nrho cov bioavailability ntawm hesperidin 95%.
Theem II Metabolism hauv Enterocytes thiab Hepatocytes
Hesperidin 95% Mus los ntawm ntau ntawm theem II ua nyob rau hauv ob qho tib si enterocytes thiab hepatocytes tom qab nws coj. Glucuronidation thiab sulfation yog cov kev sib txuas tseem ceeb uas tshwm sim hauv cov txheej txheem no. Enzymes zoo li Dusts thiab Sults ua lub luag haujlwm tseem ceeb hauv kev ua kom ntev cov kev cuam tshuam no. Cov kev hloov enzyme no muaj qhov cuam tshuam loj ntawm Hesperidin ntawm Hesperidin 95% thiab nws tau ua haujlwm hauv lub cev, thiab thaum kawg lawv tau yaug tawm ntawm lub cev. Kev sib txawv ntawm cov kev sib txawv hauv cov enzymes koom nrog tuaj yeem ua cov txheej txheem metabolic ua haujlwm tsawg dua lossis ntau dua hauv cov neeg sib txawv. Qhov no tuaj yeem ua rau muaj kev sib txawv ntawm qhov 95% ua haujlwm thiab ua li cas bioavailable nws yog. Nws yog ib qho tseem ceeb heev kom nkag siab txog cov kev sib txuam no txhawm rau twv seb hesperidin li cas 95% yuav ua haujlwm hauv cov pab pawg sib txawv ntawm cov neeg.
Deconjugation los ntawm plab microbiota
Hauv kev nthuav nthuav, cov kev hloov enzyme hloov uas cuam tshuam rau 95% nqus ntawm hesperidin tsis yog tsuas yog txwv rau tib neeg enzymes. Los ntawm kev ua cov txheej xwm deconjugation, lub plab microbiome tseem muaj pab txhawb rau tus txheej txheem no. Muaj cov kab mob hauv lub plab uas muaj cov enzymes uas tuaj yeem txiav cov conjugates uas tau ua thaum lub sij hawm II metabolism. Qhov no tuaj yeem pab ua kom muaj kev nquag ua ib daim ntawv aggercone dua. Cov microbation no los ntawm cov microbes tuaj yeem tshwm sim hauv lub plab, muab cov tshuaj muaj txiaj ntsig los ntawm hesperidin 95% thib ob lub caij nyoog yuav tsum nqus tau. Ntau txheej txheem no tshwm sim yog nyob ntawm hom thiab kev ua ntawm cov kab mob hauv ib tus neeg lub plab. Qhov no qhia tau hais tias yuav ua li cas tus tswv tsev enzymes, cov kab mob plab thiab zaub mov ua ke cuam tshuam li cas Bioavailable hesperidin 95% yog thaum kawg.
Yuav ua li cas tsim cov tswv yim txhim kho hesperidin 95% nqus?
Cov tswv yim Naneyencapsulation
Noonsencapsulation tau dhau los ua txoj kev muaj peev xwm ua kom Hesperidin 95% yooj yim dua rau lub cev kom nqus thiab siv. Hauv txoj kev no, 95% ntawm Hesperidin yog ntim rau hauv cov khoom me me uas feem ntau yog ua los ntawm cov khoom siv rov ua thiab cov lipids. Nanyencapsulation muaj peev xwm ua kom 95% ntawm hesperidin los ntawm kev tawg hauv qhov nyuaj ib puag ncig ntawm lub plab thiab ua kom nws txav mus ntxiv rau cov hnyuv paug hnoos. Liposomes, khoom lipid nanoparticles, thiab polymeric nanoparticles yog qee txoj hauv kev uas tau saib rau hauv kev xa 95% ntawm hesperidin. Cov mixtures tau qhia tias Hesperidin 95% yaj, nyob ruaj khov, thiab tab tom coj los ntawm cov hlwb zoo dua. Qhov no tuaj yeem ua rau nqus tau zoo thiab tshuaj tau txais txiaj ntsig zoo.
Emulsion -} raws cov khoom xa tawm
Lwm txoj hauv kev zoo los txhim kho qhov nqus ntawmHesperidin 95%yog siv cov kev xa khoom raws li emulsions. Nyob rau hauv cov tshuab no, hesperidin 95% feem ntau yog tov nrog cov roj theem thiab tom qab ntawd ua ke hauv {}} dej emulsions lossis nanoemulsions. Vim tias cov sib xyaw no yog lipophilic, lawv tuaj yeem ua kom hesperidin 95% ntau soluble thiab permicable barliers. Nanoemulsions tseem muaj cov tee me me, uas txhais tau tias muaj ntau thaj chaw thaj chaw muaj rau kev nqus. Qhov no tuaj yeem ua rau kom zoo dua solubility. Qee qhov kev tshawb fawb kuj tau saib rau tus kheej - emulsifyure yeeb tshuaj txias cov tshuab (sedds) rau hesperidin 95%. Cov kab ke no ua kom cov roj zoo li roj- hauv- dej emulsions, uas ua rau kev nqus tau zoo dua.
Complexation nrog cyclodextrins
Siv cyclodextrins los tsim cov complexes yog txoj hauv kev ntse los txhim kho cov uptake ntawm 95% ntawm hesperarin. Nws yog ua los ntawm puag ncig oligosaccharides uas muaj ib lub hydrophilic sab nraud thiab ib hydrophobic sab hauv. Lawv tuaj yeem koom nrog lipophilic molecules zoo li hesperidin 95% ua rau suav nrog cov khoom. Qhov kev nyuaj no tuaj yeem ua hesperidin 95% ntau dua ruaj khov thiab soluble hauv dej, uas tuaj yeem pab nws yaj thiab yuav nqus tau zoo hauv lub plab zom mov. Ntau hom cyclodextrins, zoo li {{{{{} cyclodextrin thiab nws txoj kev hloov pauv, tau saib rau hauv lawv lub peev xwm tso 95% ntawm hesperidin. Cov complex no yuav ua ntau dua li ua kom cov tshuaj ntau soluble. Lawv kuj tseem tuaj yeem zais qhov saj thiab ua kom nws los ntawm oxidizing, ntawm lwm yam. Qhov no ua rau lawv zoo meej rau qhov ncauj hloov ntawm hesperidin 95%.
Tag
Yog li, ntau yam tuaj yeem hloov tau zoo npaum li casHesperidin 95%yog coj mus rau hauv thiab tawg. Tej yam zoo li cov kab mob hauv plab, hloov cov enzymes, thiab txoj kev vitamin yog ib co ntawm cov no. Yog tias koj xav tau cov neeg zoo tshaj plaws ntawm cov vitamin, koj yuav tsum paub txog tej no. Hesperidin 95% tuaj yeem coj thiab siv tau zoo dua yog tias nws tau ua kev siv cov txuj ci tam sim no uas coj mus rau hauv cov kab mob plab thiab enzyme. Raws li muaj kev kawm ntau dua nyob rau thaj chaw no, peb tuaj yeem cia siab tias yuav muaj ntau txoj hauv kev muaj tswv yim los muab hesperidin 95%. Cov neeg siv khoom noj qab haus huv yuav zoo dua vim qhov no.
siab zooHesperidin 95%
NtawmLonierhlerb, Peb tau cog lus rau kev nce qib kev tshawb fawb qab cov khoom lag luam zoo li Hesperidin 95%. Nrog peb lub xeev - ntawm {}}} Cov artic modern thiab huv siab tshaj plaws ntawm peb hesperidin 95% extract. Peb cov khoom lag luam nrov nyob rau hauv 40 lub teb chaws, suav nrog Tebchaws Europe, thiab Australia, ua tsaug rau peb txoj kev mob siab rau kom zoo thiab tsim kho tshiab. Yog xav paub ntxiv txog peb hesperidin 95% cov khoom lag luam lossis los tham txog cov kev cai kev cai, thov hu rau peb ntawminfo@lonierherb.com.
Cov FAQ
Q: Dab tsi yog hesperidin 95%?
A: Hesperidin 95% yog ib daim ntawv ntau ntawm hesperidin, flavonoid glycoside pom ib txwm nyob rau hauv cov txiv ntoo txiv ntoo. Nws yog extracted thiab purified kom ua tiav 95% qib purity.
Q: Ua li cas cov me me microbiota cuam tshuam hesperidin 95% nqus?
A: Out microbiota plays lub luag haujlwm tseem ceeb los ntawm metabolizing hesperbable form, hesperetin, thiab los ntawm kev tsim cov me me metabolites uas tuaj yeem pab nws cov teebmeem kev noj qab haus huv.
Q: Dab tsi yog qhov tseem ceeb enzymatic kev sib hloov tau koom nrog hesperidin 95% bioavailability?
A: Lub ntsiab enzymatic hloov dua xws li - glucosidase kev ua si hauv interocytes thiab deconjugation, thiab deconjugation los ntawm plab microbiota enzymes.
Q: Yuav tuaj yeem Noonsencapsulation txhim kho Hesperidin 95% nqus?
A: Yog, Nanoencaptulation tuaj yeem txhim kho hesperidin 95% nqus los ntawm kev tiv thaiv nws los ntawm kev tiv thaiv thiab muab nws thauj thoob plaws lub plab hnyuv epithelium.
Ntawv Sawv cev
1. González - sarrías, A., li al. (2017). "Hesperidin thiab nws cov metabolites hesperetin thiab hesperetin {{7-o-glucuronide: nqus, cov metabolism, thiab bioactivity hauv tib neeg." Phau ntawv Journation ntawm cov neeg ua liaj ua teb thiab 65 (32), 6823-6830.
2. Erlund, I., li al. (2001). "Plasma kinetics thiab tso zis ua pov thawj ntawm cov flavanones naringenin thiab hesperetin nyob rau hauv tib neeg tom qab noj kua txiv kab ntxwv thiab txiv kab ntxwv qaub." Phau Ntawv Xov Xwm ntawm Khoom Noj, 131 (2), 235-241.
3. Marin, L., li al. (2015). "Bioavailability ntawm kev noj haus polyphenols thiab plab microbiota metabolism: Antimicrobial cov yam ntxwv." Kev Tshawb Fawb Biomed Thoob Ntiaj Teb, 2015, 905215.
4. Balges, G., li al. (2018). "Cov xyoob xyoob ntawm kev noj zaub mov anthocyanins thiab flavanones." Kev hais plaub ntawm cov khoom noj khoom haus, 77 (3), 227-235.
5. Manach, C., li al. (2005). "Bioavailability thiab biofficacy ntawm polyphenols hauv tib neeg. I. Rov Los Saib 97 Kev Kawm Txog 97 Bioavailotties." Cov phau ntawv Asmeskas ntawm cov khoom noj khoom haus, 81 (1), 230s-2430s.
6. Shulman, M., li al. (2011). "Ua kom zoo ntawm Naringenin Bioavailability los ntawm cov nyom nrog hydroxypropoyl {}} cyclodextrin." PLOS IB, 6 (4), E18033.
