Bakuchiol 98 percent Before and After

Bakuchiol 98 percent transliterated from its English name Bakuchiol (BAK), is the mature fruit of the leguminous plant Psoraleae. The main chemical components of psoralen are coumarins, terpene phenols, flavonoids, etc. Bakuchiol, also known as broken paper phenol, belongs to isoprenyl; its content is higher in psoralen seeds. As early as a few years ago, bakuchiol has been widely sought after overseas and included in the catalog of cosmetic raw materials. Many laboratory studies and clinical trials have found that it has potent anti-inflammatory activity, can improve skin pigmentation, and has strong anti-aging and whitening effects.

On the one hand, bakuchiol acts on keratinocytes; on the other hand, it stimulates and enhances the activity of fibroblasts deep into the subcutaneous area to stimulate the production of collagen, repair wounds, and regenerate skin. At the same time, bakuchiol reduces the levels of prostaglandin E2 and macrophage migration inhibitory factor, further inhibits skin aging caused by inflammation and reactive oxygen species, and relieves collagen degradation. Bakuchiol can significantly increase the metabolic level of water-soluble tetrazolium and accelerate fibronectin production.

1. Anti-inflammatory

Bakuchiol Oil can reduce the production of cells and factors such as NO (nitric oxide), PE2 (prostaglandin 2), LTB4 (leukotriene B4), and TxB2 (thromboxane B2), thereby inhibiting inflammatory manifestations (redness, swelling, Five characteristics of heat, pain, and dysfunction).

2. Antibacterial

3. Anti-oxidation

Bakuchiol Liquid is a more robust fat-soluble antioxidant than vitamin E. It can inhibit tBH-, CCl4-, D-GalN-, and NADH-induced lipid peroxidation and can also inhibit lipid peroxidation induced by various oxidative free radicals, Lipid peroxidation, such as Cl3CO2, LOO-, DPPH free radicals and OH-, thereby reducing the damage of free radicals to DNA chains, reducing the activity of enzymes in the plasma membrane, protein denaturation, increased membrane fragility, and changes in membrane structure so that it can Reduce the appearance of wrinkles and age spots.

4. Anti-Aging

Lonier Bakuchiol can enhance the activity of human skin fibroblasts, promote the increase of skin TIMP-2 and decrease of MMP-1, thereby reducing the decomposition of skin collagen and, at the same time, promoting the synthesis of skin collagen, thus achieving anti-aging effects. Bakuchiol can encourage the proliferation of ESF-1 cells, promote the expression of collagen and matrix metalloproteinase inhibitor mRNA, and inhibit the expression of matrix metalloproteinase mRNA, thereby exerting the effect of anti-aging skin.

5. Whitening

Bakuchiol has an inhibitory effect on tyrosine mycophenolate and diphenols. Bakuchiol has a more apparent inhibitory effect on tyrosinase than arbutin in the low concentration range and can become natural tyrosine Acidase inhibitor potential. Bakuchiol has a potential inhibitory effect on the formation of melanin in B16 mouse melanoma cells induced by -melanin without cytotoxicity and can treat post-inflammatory hyperpigmentation of the skin.

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